Circular RNA (circRNA)
Next-Generation RNA Platform for Stable Gene Expression
Circular RNA is a highly stable alternative to linear mRNA, enabling sustained protein expression and exceptional molecular robustness. Its covalently closed structure resists exonuclease degradation, making it ideal for gene expression and therapeutic research.
Structural Stability
circRNA forms a covalently closed loop, lacking 5′ and 3′ ends, which protects it from exonuclease degradation. This confers a longer intracellular half-life and sustained protein expression.
Protein Expression
Engineered circRNAs with internal ribosome entry sites (IRES) can drive stable and prolonged protein production, often outperforming traditional mRNA constructs.
Functional Genomics
circRNAs are valuable for investigating gene regulation, microRNA sponging, protein binding, and post-transcriptional control mechanisms.
Synthetic Biology
circRNA serves as a robust genetic element in synthetic biology, enabling durable RNA circuits and regulatory systems for molecular engineering.
Therapeutic Research
With reduced immunogenicity and enhanced stability, circRNA is being explored for RNA-based therapeutics, gene therapy, and next-generation vaccine platforms.
Custom circRNA Synthesis
High-quality synthesis ensures pure and functional circRNA for research applications, including sequence optimization, enzymatic circularization, and quality validation.
Circular RNA (circRNA)
Next-Generation RNA Platform for Stable Gene Expression
Circular RNA is a highly stable alternative to linear mRNA, enabling sustained protein expression and exceptional molecular robustness. Its covalently closed structure resists exonuclease degradation, making it ideal for gene expression and therapeutic research.
Structural Stability
circRNA forms a covalently closed loop, lacking 5′ and 3′ ends, which protects it from exonuclease degradation. This confers a longer intracellular half-life and sustained protein expression.
Protein Expression
Engineered circRNAs with internal ribosome entry sites (IRES) can drive stable and prolonged protein production, often outperforming traditional mRNA constructs.
Functional Genomics
circRNAs are valuable for investigating gene regulation, microRNA sponging, protein binding, and post-transcriptional control mechanisms.
Synthetic Biology
circRNA serves as a robust genetic element in synthetic biology, enabling durable RNA circuits and regulatory systems for molecular engineering.
Therapeutic Research
With reduced immunogenicity and enhanced stability, circRNA is being explored for RNA-based therapeutics, gene therapy, and next-generation vaccine platforms.
Custom circRNA Synthesis
High-quality synthesis ensures pure and functional circRNA for research applications, including sequence optimization, enzymatic circularization, and quality validation.
🔥 Explore Custom circRNA Services
🔥 Explore Custom circRNA Services
🔥 Explore Custom circRNA Services
🔥 Explore Custom circRNA Services
Explore AffiRNA circRNA Services
Discover AffiRNA’s advanced circRNA custom synthesis platform, designed for stable gene expression, functional studies, and cutting-edge RNA research. Customize your sequences and unlock the full potential of circular RNA in your experiments.
Visit AffiRNA WebsiteExplore AffiRNA circRNA Services
Discover AffiRNA’s advanced circRNA custom synthesis platform, designed for stable gene expression, functional studies, and cutting-edge RNA research. Customize your sequences and unlock the full potential of circular RNA in your experiments.
Visit AffiRNA Website